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I can feel my health improving, not just mentally, I can now even do house
chores like I used to. With every follow up visit, the data proves my recovery.
For someone with fairly advanced stage cancer, I never dreamed CAR-T would
bring such results. Now I'm enjoying every day I'm spending with my family.
“

Mr. Hu
Hepatocellular Carcinoma BCLC Staging B
Received CAR-T therapy on September 25, 2020

I can feel my health improving, not just mentally,
I can now even do house chores like I used to.
With every follow up visit, the data proves my
recovery. For someone with fair advanced stage
cancer, I never dreamed CAR-T would bring
such results. Now I'm enjoying every day I'm
spending with my family.
“

胡先生
Hepatocellular Carcinoma BCLC Staging B
Received CAR-T therapy on September 25, 2020

When the doctor said "You have recovered" in the phone, I was shocked.
This is the first time I've heard anything like that after years and countless
treatments since I've been diagnosed with liver cancer. CAR-T therapy
gave me the will to live!
“

Mrs. Fang
Hepatocellular Carcinoma BCLC Staging C
Received CAR-T therapy on January 25, 2021

When the doctor said "You have recovered"
in the phone, I was shocked. This is the first
time I've heard anything like that after years
and countless treatments since I've been
diagnosed with liver cancer. CAR-T therapy
gave me the will to live!
“

胡先生
Hepatocellular Carcinoma BCLC Staging C
Received CAR-T therapy on January 25, 2021

We are a clinical stage biotech company focused on creating innovative cell therapies.
We strive to become the world leader in immunotherapy in cancer. With scientific excellence and our social value, we aim to overcome the bottleneck in cancer treatment efficacy with partners around the world.
Our goal is to provide patients with more treatment option, relieve suffering, improving the lives of patients and their families, and bring hope to cancer patients around the world.

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Return to health, Restart vitality

Founded in 2015, with the long-term strategy of developing innovative and clinically valuable immunotherapies. Oricell Therapeutics focuses on a wide range of indications with unmet clinical needs, including hepatocellular carcinoma, multiple myeloma, gastric carcinoma, pancreatic carcinoma, cholangiocarcinoma and ovarian carcinoma. We are committed to developing cost-effective, long-lasting and meaningful cellular drugs for the unmet clinical needs in the world, and we hope our advancement and exploration of life sciences can make a visible difference to the lives of patients, helping them "return to health, restart vitality".

  • Our Mission

    Dedicated to developing effective and accessible immunotherapeutics
    and extend the life of cancer patients.

    Dedicated to developing effective
    and accessible immunotherapeutics
    and extend the life of cancer patients.

  • Our Vision

    To become a global leader in innovation-drive
    novel immunotherapies.

  • Our Values

    Patient-first, Scientific Excellence,
    Integrity, Synergy and Collaboration

Core Team

Helen Yang, EMBA

Co-founder/Chairperson/CEO

Helen Yang, EMBA

Co-founder/Chairperson/CEO

Helen is a successful business leader with 3 decades of operations and management experience. She has a remarkable track record, having served as a C-suite manager for two publicly listed companies and one private company across various industries. Additionally, Helen co-founded and successfully led the IPO of Canature (300272).
Helen received her Bachelor degree at Beijing Institute of Technology, EMBA at CEIBS and is a Ph.D. candidate at Tongji University in China.

Peter He, Ph.D.

Co-founder & CSO

Peter He, Ph.D.

Co-founder & CSO

Peter is a highly accomplished molecular biologist and immunologist, boasting over 20 years of extensive expertise in the field. He remains unwavering in his dedication to advancing the scientific domain through pioneering research in cell development and metabolism, with a specific emphasis on tumor immune microenvironment. Notably, he prioritizes innovation and has effectively guided his team in creating a cutting-edge technology platform for Oricell.
Peter received a doctoral degree in molecular biology and genetics at Second Military Medical University in China and completed his post-doctoral training at University of Medicine and Dentistry of New Jersey.

Weidong Cui, Ph.D.

CTO, GM Oricell (US)

Weidong Cui, Ph.D.

CTO, GM Oricell (US)

Dr. Cui brings over 25 years of CMC experience. Prior to joining Oricell, Dr. Cui served as the CTO of Fosun Kite, led the tech transfer, NDA submission and commercial launch of the first autologus CAR-T therapy Yescarta® (Axi-Cel) in China. Before Fosun Kite, Dr. Cui also served in various senior management and scientific roles in MedImmune and AstraZeneca.
Dr. Cui received his Ph.D. at SUNY ESF Syracuse University and completed his post-doctoral training at UCSF.

History

2023

  • · AugustOriCAR-017 CAR-T Therapy Clears IND Hurdle, Paving the Way for Global Impact
  • · MayOri-C101 Clinical Study Begins Enrolling Subjects with Hepatocellular Carcinoma
  • · FebruaryClosed $45M Series B1 Financing Round Led by RTW and Qatar Investment Authority
  • · JanuaryOriCAR-017 follow-up data published in The Lancet Haematology

2022

  • · JuneReports OriCAR-017 Phase I POLARIS study Data in Oral Presentation at ASCO 2022
  • · MayOriCAR-017 Clinical Data Selected for Oral Presentation at EHA 2022 Congress
    Selected in Shanghai Professional, Refined, Specialized, Novel Businesses List
  • · AprilCAR-T product candidate OriCAR-017 clinical data abstract selected for oral presentation at ASCO 2022
  • · MarchAnnounced the appointment of Dr. Weidong Cui as Chief Technology Officer

2021

  • · AugustOricell Therapeutics was the responsible unit for the biomedical technology support special project under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality
  • · JuneThe first CAR-T cell product targeting liver cancer developed by OriCell Therapeutics made its debut at ASCO
  • · MayOricell Medical Technology Co., Ltd. officially changed its name to "OriCell Therapeutics (Shanghai) Co., Ltd."

2019

  • · DecemberReceived the pre-A round of exclusive funding from Qiming Venture Partners
  • · NovemberBecame a co-construction unit of Shanghai Cell Therapy Clinical Transformation Engineering Technology Center
    Became one of the funded key technology start-up enterprises in Pudong New Area
  • · AprilOriCell Medical was the responsible unit for the biomedical technology support special project under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality

2017

  • · JulyOriCell Medical in collaboration with Zhongshan Hospital carried out a series of clinical trials of the cell therapy technologies (among which CAR-T was the most notable) at the Zhongshan-OriCell Therapy Center, which was jointly constructed by the two units
  • · MayShanghai Long March Hospital (LMH) and Primary Medicine officially launched the "LMH-Primary Energy Cell Clinical Research Center" in Shanghai Long March Hospital (LMH).

2015

  • · FebruaryOriCell Medical was founded by OriginCell Group; Co-founder Dr. He Xiaowen serving as the chief scientist

2022

  • · NovemberOricell and Cytiva Signs Strategic Cooperation Agreement at the 5th China International Import Expo
  • · OctoberGPRC5D CAR-T receives Orphan Drug Designation from FDA
  • · SeptemberReceives Implied License from NMPA for Ori-C101 IND Application
  • · AugustRaises Over $120 Million in Series B Financing

2021

  • · DecemberOricell Therapeutics once again receives "High and New Technology Enterprise" recognition since November 2018
  • · NovemberOricell Therapeutics' data from the first IIT in metastatic osteosarcoma to the lung was accepted for poster presentation at the 2021 CSCO Annual Meeting
  • · SeptemberOricell Therapeutics' data from the first IIT in metastatic osteosarcoma to the lung was accepted for an oral presentation at the 2021 CSCO Annual Meeting
    Oricell Therapeutics was the responsible unit for the technology innovation funding project for small and medium-sized technology-based enterprises under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality

2020

  • · DecemberReceived the A round of financing of 202.138 million, an investment led by SPINNOTEC, Zhangjiang Technology Venture Capital, and Yijing Capital, followed by Qiming Venture Partners and Osen Assets
    Established the Shanghai Academician (Expert) Workstation<
  • · NovemberEstablished the Pudong New Area Enterprise Postdoctoral Research Workstation Substation
  • · OctoberWon the first prize in the 13th "Zhangjiang Pharma Valley Cup" Biomedicine Experimental Skill Competition
  • · JuneResponsible unit for the technology innovation funding project for small and medium-sized technology-based enterprises under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality
    Reached a global development agreement regarding the independently-developed bispecific antibody with ANTENGENE (6996.HK), with a potential worth of 142 million USD

2018

  • · NovemberRecognized as a High and New Technology Enterprise
    Received funding from the 2018 Pudong New Area Science and Technology Development FundThe Secretary-General of the Nobel Prize Committee visited OriCell Medical
  • · OctoberAttended the 2018 Chinese Conference on Translational Medicine and presented its independent R&D results in multiple fields
  • · JuneResearch results for CAR-T in liver cancer were published in the authoritative journal Protein & Cell
  • · MaySigned a strategic cooperation agreement with an emerging enterprise in the domestic CAR-T industry, Beijing Yimiaoshenzhou Medical Technology Co., Ltd.
  • · MarchThe Ministry of Science and Technology approved OriCell Medical as the principal institution to continue and complete the research project of the 973 Program titled "Research on New Intervention Strategies for Ankylosing Spondylitis"

2016

  • · MayEstablished the CAR-T technology platform with high memory and high vitality
  • · FebruaryExpanded R&D team

2023

  • · AugustOriCAR-017 CAR-T Therapy Clears IND Hurdle, Paving the Way for Global Impact
  • · MayOri-C101 Clinical Study Begins Enrolling Subjects with Hepatocellular Carcinoma
  • · FebruaryClosed $45M Series B1 Financing Round Led by RTW and Qatar Investment Authority
  • · JanuaryOriCAR-017 follow-up data published in The Lancet Haematology

2022

  • · JuneReports OriCAR-017 Phase I POLARIS study Data in Oral Presentation at ASCO 2022
  • · MayOriCAR-017 Clinical Data Selected for Oral Presentation at EHA 2022 Congress<br>Selected in Shanghai Professional, Refined, Specialized, Novel Businesses List
  • · AprilCAR-T product candidate OriCAR-017 clinical data abstract selected for oral presentation at ASCO 2022
  • · MarchAnnounced the appointment of Dr. Weidong Cui as Chief Technology Officer

2021

  • · AugustOricell Therapeutics was the responsible unit for the biomedical technology support special project under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality
  • · JuneThe first CAR-T cell product targeting liver cancer developed by OriCell Therapeutics made its debut at ASCO
  • · MayOricell Medical Technology Co., Ltd. officially changed its name to "OriCell Therapeutics (Shanghai) Co., Ltd."

2019

  • · DecemberReceived the pre-A round of exclusive funding from Qiming Venture Partners
  • · NovemberBecame a co-construction unit of Shanghai Cell Therapy Clinical Transformation Engineering Technology Center<br>Became one of the funded key technology start-up enterprises in Pudong New Area
  • · AprilOriCell Medical was the responsible unit for the biomedical technology support special project under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality

2017

  • · JulyOriCell Medical in collaboration with Zhongshan Hospital carried out a series of clinical trials of the cell therapy technologies (among which CAR-T was the most notable) at the Zhongshan-OriCell Therapy Center, which was jointly constructed by the two units
  • · MayShanghai Long March Hospital (LMH) and Primary Medicine officially launched the "LMH-Primary Energy Cell Clinical Research Center" in Shanghai Long March Hospital (LMH).

2015

  • · FebruaryOriCell Medical was founded by OriginCell Group; Co-founder Dr. He Xiaowen serving as the chief scientist

2022

  • · NovemberOricell and Cytiva Signs Strategic Cooperation Agreement at the 5th China International Import Expo
  • · OctoberGPRC5D CAR-T receives Orphan Drug Designation from FDA
  • · SeptemberReceives Implied License from NMPA for Ori-C101 IND Application
  • · AugustRaises Over $120 Million in Series B Financing

2021

  • · DecemberOricell Therapeutics once again receives "High and New Technology Enterprise" recognition since November 2018
  • · NovemberOricell Therapeutics' data from the first IIT in metastatic osteosarcoma to the lung was accepted for poster presentation at the 2021 CSCO Annual Meeting
  • · SeptemberOricell Therapeutics' data from the first IIT in metastatic osteosarcoma to the lung was accepted for an oral presentation at the 2021 CSCO Annual Meeting<br>Oricell Therapeutics was the responsible unit for the technology innovation funding project for small and medium-sized technology-based enterprises under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality

2020

  • · DecemberReceived the A round of financing of 202.138 million, an investment led by SPINNOTEC, Zhangjiang Technology Venture Capital, and Yijing Capital, followed by Qiming Venture Partners and Osen Assets<br>Established the Shanghai Academician (Expert) Workstation<
  • · NovemberEstablished the Pudong New Area Enterprise Postdoctoral Research Workstation Substation
  • · OctoberWon the first prize in the 13th "Zhangjiang Pharma Valley Cup" Biomedicine Experimental Skill Competition
  • · JuneResponsible unit for the technology innovation funding project for small and medium-sized technology-based enterprises under the "Science and Technology Innovation Action Plan" of the Science and Technology Commission of Shanghai Municipality<br>Reached a global development agreement regarding the independently-developed bispecific antibody with ANTENGENE (6996.HK), with a potential worth of 142 million USD

2018

  • · NovemberRecognized as a High and New Technology Enterprise<br>Received funding from the 2018 Pudong New Area Science and Technology Development FundThe Secretary-General of the Nobel Prize Committee visited OriCell Medical
  • · OctoberAttended the 2018 Chinese Conference on Translational Medicine and presented its independent R&D results in multiple fields
  • · JuneResearch results for CAR-T in liver cancer were published in the authoritative journal Protein & Cell
  • · MaySigned a strategic cooperation agreement with an emerging enterprise in the domestic CAR-T industry, Beijing Yimiaoshenzhou Medical Technology Co., Ltd.
  • · MarchThe Ministry of Science and Technology approved OriCell Medical as the principal institution to continue and complete the research project of the 973 Program titled "Research on New Intervention Strategies for Ankylosing Spondylitis"

2016

  • · MayEstablished the CAR-T technology platform with high memory and high vitality
  • · FebruaryExpanded R&D team
More

Proprietary and Innovative Technology Platforms

Proprietary, unique, adaptive CAR-T platform
Focusing on developing first-in-class and best-in-class immunotherapies

More

Diverse Pipeline

More than 10 CAR-T product pipelines
4 in clinical validation stage with 2 in registered phase I clinical trial

More

Helen Yang, EMBA

Co-founder/Chairperson/CEO

Helen is a successful business leader with 3 decades of operations and management experience. She has a remarkable track record, having served as a C-suite manager for two publicly listed companies and one private company across various industries. Additionally, Helen co-founded and successfully led the IPO of Canature (300272).
Helen received her Bachelor degree at Beijing Institute of Technology, EMBA at CEIBS and is a Ph.D. candidate at Tongji University in China.

Peter He, Ph.D.

Co-founder & CSO

Peter is a highly accomplished molecular biologist and immunologist, boasting over 20 years of extensive expertise in the field. He remains unwavering in his dedication to advancing the scientific domain through pioneering research in cell development and metabolism, with a specific emphasis on tumor immune microenvironment. Notably, he prioritizes innovation and has effectively guided his team in creating a cutting-edge technology platform for Oricell.
Peter received a doctoral degree in molecular biology and genetics at Second Military Medical University in China and completed his post-doctoral training at University of Medicine and Dentistry of New Jersey.

Weidong Cui, Ph.D.

CTO, GM Oricell (US)

Dr. Cui brings over 25 years of CMC experience. Prior to joining Oricell, Dr. Cui served as the CTO of Fosun Kite, led the tech transfer, NDA submission and commercial launch of the first autologus CAR-T therapy Yescarta® (Axi-Cel) in China. Before Fosun Kite, Dr. Cui also served in various senior management and scientific roles in MedImmune and AstraZeneca.
Dr. Cui received his Ph.D. at SUNY ESF Syracuse University and completed his post-doctoral training at UCSF.